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Today is a bit weird

The day has just rushed through, and I feel tired and horny in a sad way (like I want to be wanted and loved and have sex but I know it's not happening). It feels like the serotonin is out as soon as it comes in. But I only have 10 more minutes of work. Maybe I'll feel better tomorrow
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PatientlyWaiting25 · 46-50, F Best Comment
Eating bananas can help boost serotonin because they contain tryptophan, an amino acid which is essential for your body to make it. Also look after your gut, healthy food and plenty of fibre 90% of serotonin is made there.
samueltyler2 · 80-89, M
@PatientlyWaiting25 well, not exactly, the entire cycle is very complex from synthesis to destruction. in the brain serotonin is in a sort of equilibrium and is absorbed from the interneural space back into the neurons, thus deactivating its activity. I agree, I would rather exercise and eat healthy rather than take a serotonin reuptake inhibitor, but some people really need to use the medication.

If you want to delve a little further, AI helps to simplify:

Serotonin Synthesis
Serotonin, also known as 5-hydroxytryptamine (5-HT), is a neurotransmitter synthesized in the brain and gastrointestinal tract. Its synthesis occurs in two main steps:
Step 1: Hydroxylation
Tryptophan, an essential amino acid, is converted into 5-hydroxytryptophan (5-HTP) by the enzyme tryptophan hydroxylase (TPH).
Step 2: Decarboxylation
5-HTP is then converted into serotonin by the enzyme aromatic L-amino acid decarboxylase (AADC).
Location of Synthesis
Serotonin is primarily synthesized in the following locations:
Brain: Serotonergic neurons in the raphe nuclei produce serotonin that is released into the brain.
Gastrointestinal tract: Enterochromaffin cells in the gut produce serotonin that regulates digestion and other functions.
Platelets: Serotonin is also stored in platelets and released when they activate.
Regulation of Serotonin Synthesis
The synthesis of serotonin is regulated by several factors, including:
Tryptophan availability: The amount of tryptophan in the diet affects serotonin production.
TPH activity: The activity of tryptophan hydroxylase can be regulated by hormones, neurotransmitters, and drugs.
AADC activity: The activity of aromatic L-amino acid decarboxylase can also be regulated.
Importance of Serotonin Synthesis
Serotonin plays a crucial role in various physiological and psychological functions, including mood, sleep, appetite, and learning. Dysregulation of serotonin synthesis can contribute to conditions such as depression, anxiety, and insomnia.
PatientlyWaiting25 · 46-50, F
@samueltyler2 trouble is, doctors generally have five minutes to listen to you, then prescribe an ssri rather than work out why is your body in need of it. And an ssri is never the quick fix people want it to be. I know for some they are absolutely necessary even life or death and I wouldn't be against that in those circumstances but I also think, like antibiotics, they are over prescribed In many cases when nature also has an answer.
samueltyler2 · 80-89, M
@PatientlyWaiting25 unfortunately, you are correct. The modern physician lacks the empathy, and yes, time, that i was taught about. I went to medical school after reading such books as Arrowsmith, and such plays as An Enemy of the People.


 
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