Do you plan to off yourself once your body gets too crippled?
It's my plan! I don't want to be hobbling around on a walker. It's onto the next life for me, or better yet, nothing at all!!
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basilfawlty89 · 31-35, M
No, I plan to reverse aging through genetic engineering and senescent cell removal. Aging is just epigenetic changes to your body due to damage from metabolism. It has been successfully reversed in mice and the mouse lifespan doubled. It can be done in living organisms by OSKM gene editing using a modified AAV virus.
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basilfawlty89 · 31-35, M
@IstillmissEP except it is, see the work by doctors George Church and Aubrey de Grey. They have successfully rejuvenated cells and live tissues to a more youthful state. Senescent cell clearance and stem cell treatment reverses osteoarthritis in mice.
basilfawlty89 · 31-35, M
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basilfawlty89 · 31-35, M
@IstillmissEP no, that is reversing as it's actually taking genetic markers to a more youthful state. It targets all mine hallmarks of aging. It is quite possible in the future to reach 130 in the body of a 30 year old. You're surely not claiming you know more than George Church, a Harvard geneticist, biologist, chemist and author of numerous scientific papers and patents of the topic? He helped pioneer human genome sequencing and CRISPR-cas9 gene editing.
I think I know more about you on this, being that I'm a futurist and transhumanist that reads up on this constantly.
I think I know more about you on this, being that I'm a futurist and transhumanist that reads up on this constantly.
basilfawlty89 · 31-35, M
@IstillmissEP it is literally possible to take an aged skin cell, reprogram it with iPSC and send it back to an embryonic state, using OSKM it can be partially reversed without forgetting its cell identity to a youthful optimal state.
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basilfawlty89 · 31-35, M
@IstillmissEP there won't be human trials until 2025 because the FDA won't approve it if it's not shown to work in animals and cure age related diseases. It's already been tested on mice and being tested on dogs right now by Rejuvenate Bio and other companies like Salk, Turn.Bio and the SENS research foundation.
You want the FDA to be shown it cures age related diseases and reverses aging in animals first because the trials for humans take longer because of ethical reasons. George Church gas signed himself up as one of the first rest subjects.
You want the FDA to be shown it cures age related diseases and reverses aging in animals first because the trials for humans take longer because of ethical reasons. George Church gas signed himself up as one of the first rest subjects.
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basilfawlty89 · 31-35, M
@IstillmissEP well of they get sticky there are other countries with more relaxed laws on ethical human testing on volunteer basis. However most of the researchers are based in the US, Spain or Brazil. You could now technically get telomerase injected to lengthen your telomeres in Colombia, but there is a risk of oncogenic mutation.