Why wont they use the litterbox

I have 5 cats. One female and two males and two male kittens 3 months. My female has had two litters of kittens, both litters have refuse to use the litterbox.. they will go beside the boxes but thats about it.. i have changed litter, gotten new boxes, move them around (had to move one back cause mom is blind and couldn't find it) but they will not use it. What do i do?

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SW-User

Well my cat is like that, just does so the litter box when he feels like it and most of the time he does it on the floor. It's very random for him.