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How long can you stay up before you can't function?

I think when I start hitting the 21 to 22 hour mark I get super sloppy. I'm at 19 hours currently and feel pretty gross not gonna lie.
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Miram · 31-35, F
Two days is the maximum I go without any sleep/nap.

I can function after two days, but not do medical work in an emergency context. It requires in depth evaluation and analysis skills and hyperfocus. Being able to function and being efficient can be two different things.