In the 1964 Beatles movie A Hard Day's Night, Paul McCartney's grandfather delivers the line to Paul in response to him making fun of Ringo's large nose:
Grandfather: "Now, Paulie... don't mock the afflicted."
"Well, Nobody's perfect". The final line in Some Like It Hot, by Joe E. Brown after Jack Lemon (who has been in drag to escape mobsters and being wooed by Brown) finally admits that he is really a man.
