Ive officially given up

For the past few years, I've been battling depression. I've gone to numerous visits and counselling sessions, but nothing seems to be helping. I've been a horrible person, especially to my little brother, who passed away without ever havbing a meaningful moment. I attempt to forgive myself for not spending more time with him, and treating him with respect,but nothing seems to work. I have guilt dreams. My children no longer have a mother because I am unable to be myself. I believe I'vehave reached the end of the path.