i'm a little panicked as my adblockers are not working on youtube

i really hate ads, that's why adblockers have been a life saver for me on youtube for years and years now...but i just got a little panicked as went to watch a 60s music video just before and the ads are playing?? before i can watch the video....i use a windows desktop computer, my broswer is google chrome.

anyone know what i can do? i use numerous adblockers which have worked for years no problem, so not sure what's happening now??