Could it work if somebody decided to just live in different hotel/motel rooms if somebody was in the middle of figuring out what to do next

Tesla did it 🤷‍♀

Yes, it could. They might end up staying in some not so great motels on occasion, but digs is digs.

Could it? Sure, anything can happen, but will it? without knowing the people involved and the reason for the separate living situation, then I'd say it isn't exactly promising.