High potency cannabis linked to higher rates of psychosis
[b]https://neurosciencenews.com/psychosis-thc-10921/[/b]
36-40, F
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Graylight · 51-55, F
@DeluxedEdition Not one single study even states cannabis causes schizophrenia. Some studies suggest it can exacerbate symptoms and possibly plays a roll in psychosis.
Even these studies are few and far between, since cannabis can only be studies so much under its current classification. but please, present those PubMed articles.
Even these studies are few and far between, since cannabis can only be studies so much under its current classification. but please, present those PubMed articles.
DeluxedEdition · 26-30, F
@Graylight
Ortiz-Medina MB, Perea M, Torales J, Ventriglio A, Vitrani G, Aguilar L, Roncero C. Cannabis consumption and psychosis or schizophrenia development. Int J Soc Psychiatry. 2018 Nov;64(7):690-704. doi: 10.1177/0020764018801690. PMID: 30442059.
Hamilton I. Cannabis, psychosis and schizophrenia: unravelling a complex interaction. Addiction. 2017 Sep;112(9):1653-1657. doi: 10.1111/add.13826. Epub 2017 Apr 16. PMID: 28419656.
Vaucher J, Keating BJ, Lasserre AM, Gan W, Lyall DM, Ward J, Smith DJ, Pell JP, Sattar N, Paré G, Holmes MV. Cannabis use and risk of schizophrenia: a Mendelian randomization study. Mol Psychiatry. 2018 May;23(5):1287-1292. doi: 10.1038/mp.2016.252. Epub 2017 Jan 24. PMID: 28115737; PMCID: PMC5984096.
three different professional references of articles on pubmed conducted by scientists and doctors who part took in the collection and execution of information through government accessed resources. you know... the ones that don't exist according to you?
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Ortiz-Medina MB, Perea M, Torales J, Ventriglio A, Vitrani G, Aguilar L, Roncero C. Cannabis consumption and psychosis or schizophrenia development. Int J Soc Psychiatry. 2018 Nov;64(7):690-704. doi: 10.1177/0020764018801690. PMID: 30442059.
Hamilton I. Cannabis, psychosis and schizophrenia: unravelling a complex interaction. Addiction. 2017 Sep;112(9):1653-1657. doi: 10.1111/add.13826. Epub 2017 Apr 16. PMID: 28419656.
Vaucher J, Keating BJ, Lasserre AM, Gan W, Lyall DM, Ward J, Smith DJ, Pell JP, Sattar N, Paré G, Holmes MV. Cannabis use and risk of schizophrenia: a Mendelian randomization study. Mol Psychiatry. 2018 May;23(5):1287-1292. doi: 10.1038/mp.2016.252. Epub 2017 Jan 24. PMID: 28115737; PMCID: PMC5984096.
three different professional references of articles on pubmed conducted by scientists and doctors who part took in the collection and execution of information through government accessed resources. you know... the ones that don't exist according to you?
DeluxedEdition · 26-30, F
DeluxedEdition · 26-30, F
DeluxedEdition · 26-30, F
Graylight · 51-55, F
@DeluxedEdition
THINGS WE ALREDY KNOW AFTER 30-35 YEARS OF STUDY ON THIS:
*Many schizophrenics use cannabis (typically to ease symptoms of their disease).
*Cannabis shares a tenuous link with episodes of psychotics. We're well aware cannabis shares a causal relationship with psychosis. There's even a DSM diagnosis for it.
*Psychosis in not schizophrenia.
*Not all schizophrenia involves psychosis.
*Schizophrenia is a multi-faceted, very difficult disorder that requires multiple factors to manifest. There is no "this causes that" relationship.
*Schizophrenia - with rare exception - has a relatively specific time window for onset. 45-year-olds aren't toking up and becoming schizophrenic.
*There is a defined difference between the developing brains or users and those of adults.
*Many schizophrenics are poly-substance users. Cannabis is a common and easily accessible drug.
Science isn't binary. For every study you can find, I can find another. More study is needed before people who read an article in Vanity Fair start discussing the intricacies or brain chemistry and neurodevelopment.
[quote]But to prove a point:
No evidence of associations between genetic liability for schizophrenia and development of cannabis use disorder. Carsten Hjorthøj 1 2 3, Md Jamal Uddin 1 2, Theresa Wimberley, Søren Dalsgaard, David M Hougaard, Anders Børglum, Thomas Werge 2 Merete Nordentoft. PMID: 31813396 DOI: 10.1017/S0033291719003362
30 Years on: How the Neurodevelopmental Hypothesis of Schizophrenia Morphed Into the Developmental Risk Factor Model of Psychosis. Robin M Murray, Vishal Bhavsar, Giada Tripoli, Oliver Howes. Schizophrenia Bulletin, Volume 43, Issue 6, November 2017, Pages 1190–1196, https://doi.org/10.1093/schbul/sbx121
Cannabis and Psychosis Through the Lens of DSM-5
by Nathan T. Pearson * andJames H. Berry. Department of Behavioral Medicine and Psychiatry, West Virginia University School of Medicine, Morgantown, WV 26505, USA
Cannabis, nicotine and the negative symptoms of schizophrenia: Systematic review and meta-analysis of observational studies. Author links open overlay panelMichelSabeNanZhaoStefanKaiser
Hall W. Is cannabis use psychotogenic? Lancet 2006; 367: 193–95.
Macleod J, Oakes R, Copello A, et al. The psychological and social sequelae of use of cannabis and other illicit drugs by young people: systematic review of longitudinal, general population studies. Lancet 2004; 363: 1579–88.
Davey Smith G, Ebrahim S. Data dredging bias or confounding. BMJ 2002; 325: 1437–38.
Caspi A, Moffi tt TE, Cannon M, et al. Moderation of the eff ect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-Omethyltransferase gene: longitudinal evidence of a gene X environment interaction.
Biol Psychiatry 2005; 57: 1117–27. 5 Colhoun HM, McKeigue P M, Davey Smith G.
Problems of reporting genetic associations with...
The schizophrenia envirome. Os, Jim vana,b; Krabbendam, Lydiaa; Myin-Germeys, Ineza; Delespaul, Philippea Author Information Current Opinion in Psychiatry: March 2005 - Volume 18 - Issue 2 - p 141-145
Schizophrenia: Developmental Variability Interacts with Risk Factors to Cause the Disorder Nonspecific Variability-Enhancing Factors Combine with Specific Risk Factors to Cause Schizophrenia. Andrei Szoke, Baptiste Pignon, Sarah Boster, Stéphane Jamain, Franck Schürhoff. First published: 31 August 2020 https://doi.org/10.1002/bies.202000038
Cannabis, psychosis and schizophrenia: unravelling a complex interaction
Ian Hamilton. First published: 16 April 2017 https://doi.org/10.1111/add.13826[/quote]
THINGS WE ALREDY KNOW AFTER 30-35 YEARS OF STUDY ON THIS:
*Many schizophrenics use cannabis (typically to ease symptoms of their disease).
*Cannabis shares a tenuous link with episodes of psychotics. We're well aware cannabis shares a causal relationship with psychosis. There's even a DSM diagnosis for it.
*Psychosis in not schizophrenia.
*Not all schizophrenia involves psychosis.
*Schizophrenia is a multi-faceted, very difficult disorder that requires multiple factors to manifest. There is no "this causes that" relationship.
*Schizophrenia - with rare exception - has a relatively specific time window for onset. 45-year-olds aren't toking up and becoming schizophrenic.
*There is a defined difference between the developing brains or users and those of adults.
*Many schizophrenics are poly-substance users. Cannabis is a common and easily accessible drug.
Science isn't binary. For every study you can find, I can find another. More study is needed before people who read an article in Vanity Fair start discussing the intricacies or brain chemistry and neurodevelopment.
[quote]But to prove a point:
No evidence of associations between genetic liability for schizophrenia and development of cannabis use disorder. Carsten Hjorthøj 1 2 3, Md Jamal Uddin 1 2, Theresa Wimberley, Søren Dalsgaard, David M Hougaard, Anders Børglum, Thomas Werge 2 Merete Nordentoft. PMID: 31813396 DOI: 10.1017/S0033291719003362
30 Years on: How the Neurodevelopmental Hypothesis of Schizophrenia Morphed Into the Developmental Risk Factor Model of Psychosis. Robin M Murray, Vishal Bhavsar, Giada Tripoli, Oliver Howes. Schizophrenia Bulletin, Volume 43, Issue 6, November 2017, Pages 1190–1196, https://doi.org/10.1093/schbul/sbx121
Cannabis and Psychosis Through the Lens of DSM-5
by Nathan T. Pearson * andJames H. Berry. Department of Behavioral Medicine and Psychiatry, West Virginia University School of Medicine, Morgantown, WV 26505, USA
Cannabis, nicotine and the negative symptoms of schizophrenia: Systematic review and meta-analysis of observational studies. Author links open overlay panelMichelSabeNanZhaoStefanKaiser
Hall W. Is cannabis use psychotogenic? Lancet 2006; 367: 193–95.
Macleod J, Oakes R, Copello A, et al. The psychological and social sequelae of use of cannabis and other illicit drugs by young people: systematic review of longitudinal, general population studies. Lancet 2004; 363: 1579–88.
Davey Smith G, Ebrahim S. Data dredging bias or confounding. BMJ 2002; 325: 1437–38.
Caspi A, Moffi tt TE, Cannon M, et al. Moderation of the eff ect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-Omethyltransferase gene: longitudinal evidence of a gene X environment interaction.
Biol Psychiatry 2005; 57: 1117–27. 5 Colhoun HM, McKeigue P M, Davey Smith G.
Problems of reporting genetic associations with...
The schizophrenia envirome. Os, Jim vana,b; Krabbendam, Lydiaa; Myin-Germeys, Ineza; Delespaul, Philippea Author Information Current Opinion in Psychiatry: March 2005 - Volume 18 - Issue 2 - p 141-145
Schizophrenia: Developmental Variability Interacts with Risk Factors to Cause the Disorder Nonspecific Variability-Enhancing Factors Combine with Specific Risk Factors to Cause Schizophrenia. Andrei Szoke, Baptiste Pignon, Sarah Boster, Stéphane Jamain, Franck Schürhoff. First published: 31 August 2020 https://doi.org/10.1002/bies.202000038
Cannabis, psychosis and schizophrenia: unravelling a complex interaction
Ian Hamilton. First published: 16 April 2017 https://doi.org/10.1111/add.13826[/quote]
Graylight · 51-55, F
SatanBurger · 36-40, F
@Graylight [quote]More study is needed before people who read an article in Vanity Fair
[/quote]
Haha yeah because the doctor who did the study, Dr Marta Di Forti, MD, PhD
senior clinical lecturer
at Dept of Social, Genetic and Developmental Psychiatry Institute of Psychiatry Psychology and Neuroscience is really vanity fair.
[b]https://www.kcl.ac.uk/people/marta-di-forti[/b]
Hahahahahahahaha sureeeeeee.
Projection much? Go back to reading vanity fair where you belong.
[/quote]
Haha yeah because the doctor who did the study, Dr Marta Di Forti, MD, PhD
senior clinical lecturer
at Dept of Social, Genetic and Developmental Psychiatry Institute of Psychiatry Psychology and Neuroscience is really vanity fair.
[b]https://www.kcl.ac.uk/people/marta-di-forti[/b]
Hahahahahahahaha sureeeeeee.
Projection much? Go back to reading vanity fair where you belong.
DeluxedEdition · 26-30, F
@SatanBurger there are some users that are so stubborn they think they wrote history. I didn’t pull that from my ass. I smoke weed everyday multiple times a day.
A doctor told me this when he found out I was smoking. He told me he is constantly dealing with marijuana toxification which someone gets too high and freaks out and calls 911. He told me marijuana use can cause psychosis and schizophrenia over prolonged periods of time.
Sure enough I did my own research and he was absolutely right 😐
A doctor told me this when he found out I was smoking. He told me he is constantly dealing with marijuana toxification which someone gets too high and freaks out and calls 911. He told me marijuana use can cause psychosis and schizophrenia over prolonged periods of time.
Sure enough I did my own research and he was absolutely right 😐
SatanBurger · 36-40, F
@DeluxedEdition [quote]there are some users that are so stubborn they think they wrote history. [/quote]
Well it's funny to me when someone refers to the leading researcher who won an award to specifically study these things as "vanity fair." Someone who actually has experience in treating individuals who have had first episode psychosis and a PHD.
[b]https://www.kcl.ac.uk/news/dr-marta-di-forti-awarded-mrc-senior-clinical-fellowships[/b]
People are right that early stage research requires a certain amount of skepticism but that's not what this SW user is doing when referring it to vanity fair, which is basically saying it's pseudoscience. But if it's pseudoscience and just nothing was there, they wouldn't have given her money to study it.
She found things like genetic variants may play a role too, I think it's important to study if pot is going to be legalized all over.
We can't just have people developing psychosis everywhere as more and more higher strains of pot are out there as it becomes more legalized.
But it's cute how SWers all of a sudden become experts lol.
[quote]I didn’t pull that from my ass. I smoke weed everyday multiple times a day.
A doctor told me this when he found out I was smoking. He told me he is constantly dealing with marijuana toxification which someone gets too high and freaks out and calls 911. He told me marijuana use can cause psychosis and schizophrenia over prolonged periods of time.[/quote]
I had the same experience, I smoked pot for about 5 years straight pretty much. And I had to quit, ironically I was fine with lower levels for the first few years so maybe about three years and then for the last two years I moved to higher levels. I mean you could see the crystals on the pot, it was so pure and nice.
But I developed panic disorder where I didn't have panic disorder before. Still to this day I wonder if I had never smoked pot if I would be in that position. Or if I had just kept to lower levels and just smoked every now and then, I don't know if it was the direct cause but I do wonder about things.
When I stopped, my memory wasn't the same either.
Well it's funny to me when someone refers to the leading researcher who won an award to specifically study these things as "vanity fair." Someone who actually has experience in treating individuals who have had first episode psychosis and a PHD.
[b]https://www.kcl.ac.uk/news/dr-marta-di-forti-awarded-mrc-senior-clinical-fellowships[/b]
People are right that early stage research requires a certain amount of skepticism but that's not what this SW user is doing when referring it to vanity fair, which is basically saying it's pseudoscience. But if it's pseudoscience and just nothing was there, they wouldn't have given her money to study it.
She found things like genetic variants may play a role too, I think it's important to study if pot is going to be legalized all over.
We can't just have people developing psychosis everywhere as more and more higher strains of pot are out there as it becomes more legalized.
But it's cute how SWers all of a sudden become experts lol.
[quote]I didn’t pull that from my ass. I smoke weed everyday multiple times a day.
A doctor told me this when he found out I was smoking. He told me he is constantly dealing with marijuana toxification which someone gets too high and freaks out and calls 911. He told me marijuana use can cause psychosis and schizophrenia over prolonged periods of time.[/quote]
I had the same experience, I smoked pot for about 5 years straight pretty much. And I had to quit, ironically I was fine with lower levels for the first few years so maybe about three years and then for the last two years I moved to higher levels. I mean you could see the crystals on the pot, it was so pure and nice.
But I developed panic disorder where I didn't have panic disorder before. Still to this day I wonder if I had never smoked pot if I would be in that position. Or if I had just kept to lower levels and just smoked every now and then, I don't know if it was the direct cause but I do wonder about things.
When I stopped, my memory wasn't the same either.
DeluxedEdition · 26-30, F
It’s funny you mention that about developing a panic disorder because one of the more severe withdrawal symptoms is panic attacks 😧@SatanBurger
Graylight · 51-55, F
@DeluxedEdition Well, if a doctor told you....
That's way better than training, degrees and practice in the field.
Cannabis alone will [i]never[/i] cause psychosis.
That's way better than training, degrees and practice in the field.
Cannabis alone will [i]never[/i] cause psychosis.
DeluxedEdition · 26-30, F
[@Graylight i'd rather listen to my doctor than a stubborn ignorant self proclaimed know it all on the internet😹
Graylight · 51-55, F
@DeluxedEdition Nope. This is what I do. This is my wheelhouse.
85,000 medical malpractice cases per year. One doctor nearly killed me by administering a drug I couldn't take. Another nearly crippled a good friend through botched surgery. Still another just had a 2nd emergency surgery to correct what could only be improper technique the first time around.
A doctor is not a God and far more fallible.
85,000 medical malpractice cases per year. One doctor nearly killed me by administering a drug I couldn't take. Another nearly crippled a good friend through botched surgery. Still another just had a 2nd emergency surgery to correct what could only be improper technique the first time around.
A doctor is not a God and far more fallible.
DeluxedEdition · 26-30, F
@Graylight [quote]A doctor is not a God and far more fallible.[/quote] but you clearly are right😹?
Graylight · 51-55, F
SatanBurger · 36-40, F
@Graylight About that dunning-kruger meme, that's projection. How would you know you're not in that club?
I don't fully believe everything as a general rule but I think if a doctor who also sees patients for first time psychosis and got money to study the effects of pot that has on people should be studied if pot is going to be widely legalized elsewhere.
She even got an award for it so that tells me something is concerning them enough to study it.
I don't fully believe everything as a general rule but I think if a doctor who also sees patients for first time psychosis and got money to study the effects of pot that has on people should be studied if pot is going to be widely legalized elsewhere.
She even got an award for it so that tells me something is concerning them enough to study it.