How do I deal with a meddling sister in law without alienating the whold family?

She interferes all the time, in many ways. She wants to be in control and based on what happen in the past, she meddled in our marriage, parenting and etc. She is having a vacation in our home at the moment. Me and my husband argue all the time ( one of the main reason is because of her.) She interferes and she gets involved despite the fact that she doesn't have a right to do so. I have accepted her in here into my home to have a vacation but instead of respecting and at least tell his brother off, she meddles and always have something to say in every situation. I would like her to shut her mouth as she is making the situation a lot worse.