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How Big of a Deal is this Cancer Vaccine?

[media=https://m.youtube.com/watch?v=DgeRVUSuGvQ&pp=ygUHVmFjY2luZQ%3D%3D]

Moderna and Merck partnering to usher in a new frontier of medicine: mRNA vaccines along with adjuvant agents to treat cancers (in this case melanomas) and other disorders and conditions.

This is especially important given the backdrop of RFK Jr’s misinformation deluge aimed at lifesaving childhood vaccines.

This video is long, but very informative and demonstrates the potential of this technology.
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samueltyler2 · 80-89, M Best Comment
VERY! How big is the new mRNA influenza vaccine, VERY!
@samueltyler2 Hi, Doc! Yes, I share your excitement!

I am hoping to get the new Moderna flu shot if the VA stocks it. Given Collins’ and Kennedy’s influence, I am dubious…. Hopefully the higher does 65+ flu vaccine gets FDA approval.

Last year I was a Guinea pig for the old technology flu vaccine in a double blind of high dose vaccine alone vs high dose + adjuvant. I am fair sure I got the vaccine sans adjuvant but I never got the flu.
samueltyler2 · 80-89, M
@KunsanVeteran we were lucky, the match was not good last year.
@samueltyler2 True. At least, perhaps due to Kennedy’s disruption of the surveillance programs and the agenda for planning the strains to target, the gearing up of the vaccines, and the distribution.

mRNA will help with more rapid development of the vaccine, allowing shorter lead times and faster testing, acceptance, and quicker distribution. However, the “Kennedy effect” is squandering the advantage that mRNA templates (boilerplate vaccines) give us. And—if recent history is any indication of the future—his “anti-science, anti-evidence” tampering certainly isn’t over yet. Kennedy and Trump need to be removed ASAP!

As it is, we will be feeling this catastrophic regime’s ill policies and idiotic tampering for generations to come.

@PicturesOfABetterTomorrow

The three most common monoclonal antibodies used in combination with chemotherapy for NSCLC are:

Pembrolizumab (Keytruda): An immune checkpoint inhibitor targeting PD-L1.

Nivolumab (Opdivo): Another immune checkpoint blocker that boosts your immune response.

Bevacizumab (Avastin): A blood vessel growth blocker (VEGF inhibitor) used in conjunction with chemotherapy.

I haven’t found any vaccines used in treating NSCLC in the United States at this time, but I would not rule out an mRNA vaccine (in combination with other treatments [i.e. chemotherapy, radiation, anti-body-drug conjugates] especially in clinical trials).

I strongly suspect that in a relatively short time frame we will be hearing of vaccines in these roles. The companies to watch are: Moderna, Pfizer, and Merck. I don’t know if Johnson & Johnson would be a player or not.
Very interesting and could be life saving.


On another note Cuba has had a vaccine for at least some forms of lung cancer for several years now. But we allow political bullshit that doesn't matter keep from working with them.

Instead we try and starve them for ideological clout.
@PicturesOfABetterTomorrow Yes, the technology is very exciting. At this point, next we look at life extension and remission extension in phase three clinical studies soon.

One thing about the mRNA vaccines for COVID and possibly the flu—we’ve seen protection wane after several months. That’s why boosters are required. That’s maybe an advantage for rapidly mutating strains of viruses, but may affect therapeutic plans for other things like melanoma. There’s so much potential and excitement. Just having the ability to manufacture, test, and distribute new tailor made vaccines so much quicker is a game changer!

I am not familiar with the Cuban vaccine you mentioned. I do know of some monoclonal antibodies to adenocarcinomas of the lungs that may now be in clinical trials. I’ll see what I can uncover. Thanks for the “craniums up!”

 
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