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Elessar · 26-30, M
ADE has not been observed so far, after two major dominant mutations from wild type (with Delta being also partially immune-escaping), and several billion people vaccinated already.
Other respiratory pathogens (and especially, all the other endemic human CoVs) have never been seen to cause ADE either, afaik.
Also, if ADE will ever be a thing for SCV2, it'll be a problem both for vaccinees and people who recovered. Considering it's basically endemic it's only a matter of time before everyone will be exposed and will be at the same identical risk.
Other respiratory pathogens (and especially, all the other endemic human CoVs) have never been seen to cause ADE either, afaik.
Also, if ADE will ever be a thing for SCV2, it'll be a problem both for vaccinees and people who recovered. Considering it's basically endemic it's only a matter of time before everyone will be exposed and will be at the same identical risk.