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Is this true about space travel?

I was told that one of the little-known dangers for astronauts is that they cant stay too long in a zero- gravity environment;if you do so,your body will become permanently adapted to it and you will no longer be able to survive in normal gravity.Is this true?
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DrWatson · 70-79, M
Astronauts on the space station spend part of their day using exercise equipment, to maintain their muscle tone. I remember reading years ago about one astronaut who blew this off and subsequently felt awful when he returned to Earth's gravity.

But exercise does not solve everything. Numerous tests on astronauts have shown negative effects of prolonged time in zero gravity. The most recent was a study involving the Kelly twins. They were compared before and after one of them spent a long time on the space station, and the conclusion was that a good deal of deterioration had occurred in the one who went into space.
DavidT8899 · 22-25, M
@DrWatson But if a person spent an EXTREMELY long time i zero-gee,would they get to a point where they could nevet live in regular gravity for the rest of their lives?
DrWatson · 70-79, M
@DavidT8899 I do not know.