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I have flown business class on transpacific flights to Asia and it's worth the price there. Aside from comfort there are some other perks. So for instance if the plane leaves 3 hrs late and you will miss your stateside connections, the airline will typically arrange for a new flight while you are in the air. Regular passengers have to fend for themselves. If it's a shorter domestic flight consider economy plus seats with more leg room. For shorter trans Atlantic flights, consider economy plus on a foreign carrier because they are much better than on domestic airlines (US)