This is actually a serious question although I could have asked it a little nicer, I just didn't care to. *shrug*

I believe there are genetic or biological predispositions that can be either mitigated or exacerbated by experience or environment.

For example .. there is no cure for narcissism. The inherent nature of the disorder can make effective treatment a real challenge for many. However, some are able to affect meaningful improvement if so motivated.