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If it were possible

would you like to have as a pet a Chihuahua the size of a Great Dane or a Great Dane the size of a Chihuahua?
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not at all, humans have already meddled enough with wolves, need to wind down that negative tendency of humanity and leave wild animals alone, wild, and natural
@ThirstenHowl

This also means there'd be no Chihuahuas or Great Danes at all.
@rinkydinkydoink yes, it does, nor any pugs with breathing problems, nor dachsunds with disproportionately large pit bull heads which look like they would kill the mother during birth ... humans can be pretty effed up in the name of entertaining themselves
@ThirstenHowl

" humans can be pretty effed up in the name of entertaining themselves" - - solid point
@rinkydinkydoink I mean it's one thing to domesticate less advanced lifeforms such as plants (e.g., for food crops), they do not experience things like pain

but we should've never domesticated any animals, it was a gateway to messed up things like horse racing and tourist carriage rides, which can lead to injury or death for horses, all in the name of entertaining lousy humans
@ThirstenHowl

You got me looking into the whole humans/animals thing a bit more. This includes the Domestic Silkmoth and the Alpaca/Llama situation.
@rinkydinkydoink the domestic silkmoth dependence on humans is the epitome of reducing a lifeform to a mere commodity, that's extremely messed up

with alpacas and llamas, are you referring to Berserk Llama Syndrome or another issue?
@ThirstenHowl

Re llamas and alpacas, I googled "which animals and/or breeds probably wouldn't exist if it weren't for humans?" and got a huge list of animals that need human care to survive - look into Merino Sheep and their wool that never stops growing so they need constant shearing.