How would you react if a transgender tells you that you're attractive and is interested in you?

That depends on whether I'm attracted to them too, just like with a cis person saying the same thing. Being a transgender only plays into that factor. I'm not attracted to men and therefore not to female to male transgenders either. A male cross dresser or a male to female transgender who looks that way won't catch my interest. But if a male to female transgender looks like a natural female, I don't care what she was born as and it comes down to 90% personality and 10% looks.