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A new potential Malaria vaccine is under development that could save up to 300,000 lives annually.

Currently about 400,000 lives are lost per year most of them children under the age of 10.

Source:

https://www.ox.ac.uk/news/2021-04-23-malaria-vaccine-becomes-first-achieve-who-specified-75-efficacy-goal
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SW-User
Same group as behind the Astra Zeneca covid vaccine. They've been working on it for years.