What should I do?

(This is a repost. It didn’t get much traction the first time.)
So, I’ll just give a tiny bit of backstory;

My best friend values work very much, and prioritizes working hard above a lot of other things. She is an accountant, and works herself very hard.
I asked her how work was going, and she told me how stressed she is. I asked her if it would really hurt anything if some things were late because Thanksgiving is here, and she deserves that time to spend with family and have a break. And she went off being all “I work hard and do my job and come in when I’m sick or stressed because that’s what you do. Work isn’t supposed to be fun. I can’t just take off when I feel like it.” I felt like it was a dig at me, because I don’t prioritize work the way she does. I definitely value working hard, but I don’t put it above taking care of myself and spending time with family. (Not saying that she’s doing that, necessarily, I just wish she would communicate that she needs a break sometimes.) I get that things need to get done, I do. told her I didn’t mean it like that, and she goes “you know what? Not everyone gets to see their families. So I’d rather be at work than at home alone.” Which I was very confused and concerned about. She lives with her boyfriend, and her mom was supposed to be coming into town to celebrate with her. I know her mom’s dad just died about a week ago, so I wouldn’t be surprised if she is staying with family out of state, but she didn’t want to spend Thanksgiving with her mom anyway. I told her I didn’t mean to hurt her feelings, and I’ve been trying to ask her what’s going on, but she’s ignoring me. What should I do?