The most difficult time in your life...

What I want to know is your greatest Sadness, Your greatest Pain. The one word spoken to you that riped off your skin and devoured it all.
Why I want to know? I am going through a very tough time in my life. I NEED to know I am not alone! I need to know there is at least ONE that has had it harder, tougher than I. The more details the better, and thank-you.