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It depends on the type of headache tbh. I suffer from migraines and I take Topiramate to prevent migraines daily. If it feels like its just a headache ill take 3 extra strength tylenol, with a bottle of water with lemon and cucumber but if it feels like a migraine cooking up ill take an Imitrex, drink a cold coke mini then take a nap. I hope your headache subsides because migraines suck.