A second vaccine is effective too

SW-User · 2020-11-16T08:24:32-05:00

Coronavirus / COVID-19 - A second vaccine is effective too (Quote)... (3 replies).

An interim analysis released on Monday, and based on 95 patients with confirmed Covid infections, found the candidate vaccine has an efficacy of 94.5%. The company said it planned to apply to the US regulator, the Food and Drug Administration, for emergency-use authorisation in the coming weeks. In the analysis, 90 of the patients received the placebo with the remaining five the vaccine

https://www.theguardian.com/world/2020/nov/16/moderna-covid-vaccine-candidate-almost-95-effective-trials-show?CMP=Share_AndroidApp_Other

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NoahB · 31-35, M

Wait, the sample set is 5 people? Lol idk about this...

SW-User

@NoahB no

The Moderna vaccine, which is being trialled in more than 30,000 volunteers, is not expected to be available outside the US until next year. The biotech company said it would have 20m doses ready to ship in the US before the end of 2020 and hoped to manufacture 500m to 1bn doses globally next year.

So 30,000 are on the trial.

Of those 30,000 they have had (at interim analysis point, probably triggered by this number) 95 subjects with confirmed covid-19.

The drug vs placebo will be randomised equally across the trial. Half get the drug half get a placebo but nobody knows who gets what. You "unblind" the study and analysis stage and see who of the confirmed cases got the drug, who got placebo. If the drug is ineffective you would see the cases split 50/50 so 46 or 47 on each side of the study.

Here 90 are in placebo and 5 are on the drug side so it is highly effective. By now there should have been 180 cases equally spread based on this data