Metformin and Viagra show promise in Inhibiting Alzheimer’s Disease
"Alzheimer’s disease (AD) is a prevalent neurodegenerative disease predominantly affecting millions of elderly people. To date, no effective therapy has been identified to reverse the progression of AD. Metformin, as a first-line medication for Type 2 Diabetes Mellitus (T2DM), exerts multiple beneficial effects on various neurodegenerative disorders, including AD.
Evidence from clinical studies has demonstrated that metformin use contributes to a lower risk of developing AD and better cognitive performance, which might be modified by interactors such as diabetic status and APOE-ε4 status."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829062/
From the National Institute of Health:
"People who took the drug sildenafil (generic for Viagra) were less likely to develop Alzheimer’s disease. In cultured human neurons, sildenafil enhanced growth and reduced Alzheimer’s biomarkers.
The findings support further investigation of sildenafil as a possible treatment for Alzheimer’s disease."
https://www.nih.gov/news-events/nih-research-matters/viagra-associated-reduced-risk-alzheimers-disease
Evidence from clinical studies has demonstrated that metformin use contributes to a lower risk of developing AD and better cognitive performance, which might be modified by interactors such as diabetic status and APOE-ε4 status."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829062/
From the National Institute of Health:
"People who took the drug sildenafil (generic for Viagra) were less likely to develop Alzheimer’s disease. In cultured human neurons, sildenafil enhanced growth and reduced Alzheimer’s biomarkers.
The findings support further investigation of sildenafil as a possible treatment for Alzheimer’s disease."
https://www.nih.gov/news-events/nih-research-matters/viagra-associated-reduced-risk-alzheimers-disease