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deadmoon · 31-35, F
When the bristles are worn out. Or after you get sick. But the second might just be my personal preference. I hate the thought of reintroducing the same bacteria that got me sick right back into my body by continuing to use the same toothbrush.
Thexboxoneguy1991 · 31-35, M
@deadmoon there's white stuff on the bottom of two of mine