Between $350k (60hrs/week) and $200k (40hrs/week) salary?

Both. There would be other factors involved, such as the type of work, how much I enjoy it and am competent at it, how much potential for advancement there is, how much I like management and my coworkers, etc. All things being equal, I'd take the $350K for 60 hours a week for the first 15-20 years, live on $60-80K and bank the rest, and then work at $200K for the rest of my working career. By banking and investing most of the $350K, I'd be able to retire in my early 50s with plenty of time for enjoyment and retirement.