What was Anthony Bourdain depressed about?

@DownTheStreet I know my question wasn't worded in the best way. He was seemed to be so generous with his thoughts that I was thinking "given what we know.." Honestly, I like many of us, could see edges of weariness about him that's been there for a long time. I'm sure he was often lonely, disconnected from loved ones, and his drinking made him feel more depressed.

@zeeva70 Like so many brilliant creative people, he was cursed with the disease -- and it killed him.