Zombie apocalypse, obviously.
Though in all seriousness, luminosity increase as the sun ages will blow away the protective ozone layer of the atmosphere and eventually boil away the oceans and irradiate the surface. And then the expanding shell of Sol as it goes into red giant phase may very well consume the Earth entirely, though even if it doesn't the tidal forces combined with the proximity to Sol's surface increasing drag will probably tear the planet apart. Or Earth will fall away from Sol due to the loss of solar mass and then freeze.
Both are certainly an end to all habitability.