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Which one is easier to wash a lab coat or a heavy broadcloth frockcoat?

Should I wear a coat over my finest frockcoat when using the laboratory?
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Depends what kind of lab you're in and what might spill on your clothes. It would have work safety protocols.

In general, synthetic materials wash clean more easily. However they outgas carcinogenic chemicals in minute but cumulative quantities which are absorbed through the skin over time. They melt if they catch fire or if splashed with some chemicals.

A heavy broadcloth overcoat made from cotton does stain more easily. It might sometimes need to be soaked in stain removers to fit whatever the substance is (oxygen, soap, turps, bleach, salt, vinegar or baking soda followed by a rinse wash.). You could have spares, take the soiled ones to a laundromat and write off the cost against your tax assessment.
It breathes well, allowing more comfort while working