Do you disagree with the party you vote for on any big issues?

I disagree with my party's position on so-called "sanctuary cities" and illegal immigration. While it annoys me when the descendants of European immigrants get high and mighty about others choosing to immigrate here, I do accept that since the country has established sovereign borders and has immigration laws they should be followed. If they're unfair to some groups they should be changed. But they shouldn't be blatantly ignored. That's unfair to people who are going through legal channels and having to wait as a result.