Best job without experience?

Probably some smaller, part-time...
Depression doesn't pay rent. But you shouldn't lose hope. Keep looking and applying, something must pop up at some point!

Tried working for yourself ?

Window cleaning; Gardening; Growing and selling plants/flowers/vegetables ??
Kissogram !.....Laugh all you want, some folk do it !
Cab driving ?
C:V/Resume writer ?
Tutoring ?
'Life Coaching' ??

Well, you're at least 22 - what kind of work HAVE you done?
What kind of work do you enjoy?

Right now there are more jobs available than people to take them, so it shouldn't be that difficult.

Manufacturing operator is not too bad, you learn on the job

Singing! Made Rebecca Black famous.

On serious note, a general operator for factory. Kinda like picker packer but you're helping out all workers.

Night stocker positions at grocery stores can be easily learned. And some of the bigger chains like Sam's Club and Costco pay really well.

Tons of them.

Food service, construction, landscaping, retail, and the list goes on.

It depends on what you're willing to do.

Sadly, retail, in my experience.

Get a truck license