Does anybody experienced arm swelling after vaccination?

Just got my first Covid-19 vaccine shot on friday and it caused a red lump where I got my shot?

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Rokasu · 36-40, M

That's a natural body response to cuts/tears/needles. Maybe a bit of response to the inactive virus as well. Also, that needle went pretty deep into your muscle tissue. You should always expect soreness from a shot.

WonderfulOne · 22-25, F

@Rokasu Thx for the explanation, thou gh I got AstraZeneca (the best one we have here) which technology is based on mRNA, not inactive virus.

ElwoodBlues · M

@WonderfulOne Almost. From the web:
[quote]The Oxford-AstraZeneca COVID-19 vaccine uses a chimpanzee common cold viral vector known as ChAdOx1, which delivers the code that allows our cells to make the SARS-CoV-2 spike protein.[/quote]
Like J&J, AstraZeneca took an existing harmless virus, and modified its genetics to make spike protein. The injection then infects you with that still harmless virus, which, as it multiplies, helps you build anti-bodies to the spike protein.