Thoughts that leads to crazyness.

The question "title" is somewhat weird. However, I once had a friend. Who would go a bit nut case. In the way that he could not really understand it, and got him a bit irritated. When you asked him "is the universe infinity? or does it stop? if it stops what after?. So My question is this:

"Do anyone of you sometimes get thoughts that makes you irritated, confused or crazy?"

Cheers