how should you react to someone who acts 'familiar' when you don't know him / her

i've had this at times in the past with people, someone being too familiar with me when they don't know me? i find that very annoying, but more important, how should you respond to this situation? especially if you're someone like me who easily takes offence.

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FreddieUK · 70-79, M

Really annoying, especially if they are trying to sell you something.