Two years ago I had an appendectomy. The paralytic worked fine, the anesthetic, and analgesic stopped working about halfway through the surgery. I went from being out to being in tremendous pain without being able to move or anything. It was over within 30 seconds because the anesthesiologist knew real quick what was happening when my blood pressure jumped to 191/109 and my heart rate went to 184. One thing I would not wish on my worst enemy.