That is literally the worst feeling the world.

Yes. There were times in my marriage when the loneliness was so soul destroying, I’d lie in my bed at night, the unhappiness was so intense, I felt a physical pressure on my chest and thought I was having a heart attack. The stress of that time, and the sheer emotion pain I felt was unbearable at times. Stress can affect you physically.

You didn't give details but stress and anxiety can cause this feeling and yes I have felt physical symptoms from stress including a tight chest.