Why does a single benadryl always knock me out so fast? Nearly instantly.

Histamine is responsible for more than just allergies. It's also involved in wakefulness, so blocking it systemically can make you sleepy

We often give that in the hospital as a gentle sleep aid when requested. *shrug* It is what it is.

Their slogan should be “you can’t sneeze if you’re in a coma”

Benadryl and sleep aid have the same active ingredient.

Me too - I can’t take the stuff.

It has always ko me

Me too!