Trump says he's no longer taking hydroxychloroquine after WHO ended clinical traits of the drug citing high death rates in patients who took it.
A study found that patients who underwent treatment of HCQ had higher mortality rates. In a group of 96,032 patients, researchers selected 14,888 patients and put them into four treatment groups:
Chloroquine with no combination: 1,868
Chloroquine with macrolide (class of antibiotics): 3,783
Hydroxychloroquine with no combination: 3,016
Hydroxychloroquine with macrolide: 6,221
[b]Higher death risk in patients treated with drug alone or in combination[/b]
The results indicated that 9.3% of the patients i.e., about 7,530 died in the control groups in hospitals. The other group patients who underwent the treatment of hydroxychloroquine or chloroquine witnessed higher mortality rates.
The results indicated those treated with chloroquine and hydroxychloroquine without any combination reported 16.4% (307/1,868) and 18.0% (543/3,016) deaths respectively. The other groups where the patients were treated with a combination of macrolide drugs witnessed death rates at 22.2% with chloroquine (839/3,783) and 23.8% from hydroxychloroquine (1,479/6,221).
The findings also highlighted that the patients who were given the treatment of drugs witnessed heart problems like cardiac arrhythmias. It is a condition in which the lower chamber of the heart starts to beat rapidly and irregularly. The study stated, the condition was found to be more common in the groups who underwent the drug treatments.
The results highlighted, the group—hydroxychloroquine in combination with a macrolide witnessed high number of such cases, where 8% (502/6,221) of patients developed a heart arrhythmia. While 0.3% (226/81144) of such conditions was noted in the patients in the control group.
https://weather.com/en-IN/india/coronavirus/news/2020-05-27-who-clinical-trials-hydroxychloroquine-study-higher-death-risks
Chloroquine with no combination: 1,868
Chloroquine with macrolide (class of antibiotics): 3,783
Hydroxychloroquine with no combination: 3,016
Hydroxychloroquine with macrolide: 6,221
[b]Higher death risk in patients treated with drug alone or in combination[/b]
The results indicated that 9.3% of the patients i.e., about 7,530 died in the control groups in hospitals. The other group patients who underwent the treatment of hydroxychloroquine or chloroquine witnessed higher mortality rates.
The results indicated those treated with chloroquine and hydroxychloroquine without any combination reported 16.4% (307/1,868) and 18.0% (543/3,016) deaths respectively. The other groups where the patients were treated with a combination of macrolide drugs witnessed death rates at 22.2% with chloroquine (839/3,783) and 23.8% from hydroxychloroquine (1,479/6,221).
The findings also highlighted that the patients who were given the treatment of drugs witnessed heart problems like cardiac arrhythmias. It is a condition in which the lower chamber of the heart starts to beat rapidly and irregularly. The study stated, the condition was found to be more common in the groups who underwent the drug treatments.
The results highlighted, the group—hydroxychloroquine in combination with a macrolide witnessed high number of such cases, where 8% (502/6,221) of patients developed a heart arrhythmia. While 0.3% (226/81144) of such conditions was noted in the patients in the control group.
https://weather.com/en-IN/india/coronavirus/news/2020-05-27-who-clinical-trials-hydroxychloroquine-study-higher-death-risks
